GABRA1 angl Gamma aminobutyric acid type A receptor alpha1 subunit bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 5 yi hromosomi 5 Dovzhina polipeptidnogo lancyuga bilka stanovit 456 aminokislot a molekulyarna masa 51 802 6 GABRA1IdentifikatoriSimvoliGABRA1 ECA4 EIEE19 EJM EJM5 gamma aminobutyric acid type A receptor alpha1 subunit gamma aminobutyric acid type A receptor subunit alpha1 DEE19Zovnishni ID OMIM 137160 MGI 95613 HomoloGene 629 GeneCards GABRA1Pov yazani genetichni zahvoryuvannyaearly infantile epileptic encephalopathy 19 Dravet syndrome 1 Reaguye na spolukugaboxadol isonipecotic acid isoguvacine Muscimol ZK93423 flumazenil L 838417 ZK93426 bretazenil indiplon ocinaplon L 822179 methyl 6 7 dimethoxy 4 ethyl b carboline 3 carboxylate Ro 15 4513 RO4938581 alprazolam klonazepam diazepam Flunitrazepam zolpidem triazolam bicuculline picrotoxin CGS8216 2 Ontologiya genaMolekulyarna funkciya ion channel activity GABA receptor activity chloride channel activity extracellular ligand gated ion channel activity GABA gated chloride ion channel activity GABA A receptor activity transmitter gated ion channel activity involved in regulation of postsynaptic membrane potential transmembrane signaling receptor activity inhibitory extracellular ligand gated ion channel activity benzodiazepine receptor activityKlitinna komponenta integral component of membrane postsynaptic membrane membrana klitinna membrana integral component of plasma membrane sinaps chloride channel complex Mizhklitinni kontakti GABA receptor complex cytoplasmic vesicle membrane GO 0016023 cytoplasmic vesicle GABA A receptor complex GABA ergic synapse integral component of postsynaptic specialization membrane dendrite membrane neuron projection postsynapseBiologichnij proces gamma aminobutyric acid signaling pathway synaptic transmission GABAergic ion transport chloride transport cellular response to histamine chloride transmembrane transport regulation of postsynaptic membrane potential ion transmembrane transport GO 0072468 Signalna transdukciya chemical synaptic transmission regulation of membrane potential nervous system process inhibitory synapse assemblyDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez2554 14394Ensembl ENSG00000022355 ENSMUSG00000010803UniProt P14867 P62812RefSeq mRNK NM 001127648NM 000806NM 001127643NM 001127644NM 001127645NM 001127646NM 001127647NM 010250NM 001359035RefSeq bilok NP 000797NP 001121115NP 001121116NP 001121117NP 001121120NP 034380NP 001345964Lokus UCSC Hr 5 161 85 161 9 MbHr 11 42 02 42 07 MbPubMed search 3 4 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do receptoriv ionnih kanaliv hlornih kanaliv Zadiyanij u takih biologichnih procesah yak transport ioniv transport Bilok maye sajt dlya zv yazuvannya z hloridom Lokalizovanij u klitinnij membrani membrani klitinnih kontaktah citoplazmatichnih vezikulah sinapsah Literatura red Schofield P R Pritchett D B Sontheimer H Kettenmann H Seeburg P H 1989 Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits FEBS Lett 244 361 364 PubMed DOI 10 1016 0014 5793 89 80563 0 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504Primitki red Zahvoryuvannya genetichno pov yazani z GABRA1 pereglyanuti redaguvati posilannya na VikiDanih Spoluki yaki fizichno vzayemodiyut z Gamma aminobutyric acid type A receptor subunit alpha1 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 4075 angl Procitovano 31 serpnya 2017 UniProt P14867 angl Arhiv originalu za 16 veresnya 2017 Procitovano 31 serpnya 2017 Div takozh red Hromosoma 5 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title GABRA1 amp oldid 35616424
