PRODH angl Proline dehydrogenase 1 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 22 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 600 aminokislot a molekulyarna masa 68 002 5 PRODHIdentifikatoriSimvoliPRODH HSPOX2 PIG6 POX PRODH1 PRODH2 TP53I6 Proline oxidase proline dehydrogenase 1Zovnishni ID OMIM 606810 MGI 97770 HomoloGene 40764 GeneCards PRODHPov yazani genetichni zahvoryuvannyaschizophrenia 4 1 Ontologiya genaMolekulyarna funkciya oxidoreductase activity FAD binding proline dehydrogenase activityKlitinna komponenta mitohondrialna vnutrishnya membrana mitohondrialnij matriks mitohondriyaBiologichnij proces intrinsic apoptotic signaling pathway in response to oxidative stress positive regulation of cell death 4 hydroxyproline catabolic process proline catabolic process proline metabolic process proline catabolic process to glutamateDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez5625 19125Ensembl ENSG00000100033 ENSMUSG00000003526UniProt O43272 Q9WU79RefSeq mRNK NM 001195226NM 016335NM 011172RefSeq bilok NP 001182155NP 057419NP 035302Lokus UCSC Hr 22 18 91 18 94 MbHr 16 17 88 17 91 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MALRRALPALRPCIPRFVQLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQEAYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAGEDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQYQAHRAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGRPQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAYDNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHQVYFGQLLGMCDQISFPLGQAGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPAA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do oksidoreduktaz Zadiyanij u takih biologichnih procesah yak acetilyuvannya alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z FAD flavoproteyinom Lokalizovanij u mitohondriyi Literatura red Campbell H D Webb G C Young I G 1997 A human homologue of the Drosophila melanogaster sluggish A proline oxidase gene maps to 22q11 2 and is a candidate gene for type I hyperprolinaemia Hum Genet 101 69 74 PubMed DOI 10 1007 s004390050589 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Polyak K Xia Y Zweier J L Kinzler K W Vogelstein B 1997 A model for p53 induced apoptosis Nature 389 300 306 PubMed DOI 10 1038 38525Primitki red Zahvoryuvannya genetichno pov yazani z PRODH pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 9453 angl Arhiv originalu za 4 grudnya 2016 Procitovano 12 veresnya 2017 UniProt O43272 angl Arhiv originalu za 23 veresnya 2017 Procitovano 12 veresnya 2017 Div takozh red Hromosoma 22 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title PRODH amp oldid 35698485
