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ERG angl ERG ETS transcription factor bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 21 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 486 aminokislot a molekulyarna masa 54 608 4 ERGNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1SXE 4IRG 4IRH 4IRIIdentifikatoriSimvoliERG erg 3 p55 ETS related gene v ets avian erythroblastosis virus E26 oncogene homolog ETS transcription factor ETS transcription factor ERGZovnishni ID OMIM 165080 MGI 95415 HomoloGene 15848 GeneCards ERGOntologiya genaMolekulyarna funkciya DNA binding sequence specific DNA binding GO 0001131 GO 0001151 GO 0001130 GO 0001204 DNA binding transcription factor activity chromatin binding signal transducer activity GO 0001948 GO 0016582 protein binding GO 0000980 RNA polymerase II cis regulatory region sequence specific DNA binding GO 0001077 GO 0001212 GO 0001213 GO 0001211 GO 0001205 DNA binding transcription activator activity RNA polymerase II specific GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specificKlitinna komponenta citoplazma klitinne yadro RibonukleoproteyiniBiologichnij proces Diferenciaciya klitin GO 0009373 regulation of transcription DNA templated endocardial cushion development endocardial cushion to mesenchymal transition involved in heart valve formation transcription DNA templated multicellular organism development positive regulation of blood vessel remodeling protein phosphorylation proliferaciya cell migration GO 0072468 Signalna transdukciya GO 0003257 GO 0010735 GO 1901228 GO 1900622 GO 1904488 positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II GO 0044324 GO 0003256 GO 1901213 GO 0046019 GO 0046020 GO 1900094 GO 0061216 GO 0060994 GO 1902064 GO 0003258 GO 0072212 regulation of transcription by RNA polymerase IIDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez2078 13876Ensembl ENSG00000157554 ENSMUSG00000040732UniProt P11308 P81270RefSeq mRNK NM 001136154NM 001136155NM 001243428NM 001243429NM 001243432NM 001243433NM 001291391NM 004449NM 182918NM 001331025NM 133659NM 001302152NM 001302153NM 001302154NM 001302179NM 001302183RefSeq bilok NP 001129626NP 001129627NP 001230357NP 001230358NP 001230361NP 001278320NP 001317954NP 004440NP 891548NP 001289081NP 001289082NP 001289083NP 001289108NP 001289112NP 598420Lokus UCSC Hr 21 38 38 38 66 MbHr 16 95 16 95 39 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPTSHMPSHLGTYYA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak transkripciya regulyaciya transkripciyi alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z DNK Lokalizovanij u citoplazmi yadri Literatura red Rao V N Papas T S Shyam E Reddy P 1987 erg a human ets related gene on chromosome 21 alternative splicing polyadenylation and translation Science 237 635 639 PubMed DOI 10 1126 science 3299708 Reddy E S P Rao V N Papas T S 1987 The erg gene a human gene related to the ets oncogene Proc Natl Acad Sci U S A 84 6131 6135 PubMed DOI 10 1073 pnas 84 17 6131 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Dunn T Praissman L Hagag N Viola M V 1994 ERG gene is translocated in an Ewing s sarcoma cell line Cancer Genet Cytogenet 76 19 22 PubMed DOI 10 1016 0165 4608 94 90063 9 Prasad D D Rao V N Lee L Reddy E S 1994 Differentially spliced erg 3 product functions as a transcriptional activator Oncogene 9 669 673 PubMed Ichikawa H Shimizu K Hayashi Y Ohki M 1994 An RNA binding protein gene TLS FUS is fused to ERG in human myeloid leukemia with t 16 21 chromosomal translocation Cancer Res 54 2865 2868 PubMedPrimitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 3446 angl Procitovano 12 veresnya 2017 UniProt P11308 angl Arhiv originalu za 6 zhovtnya 2017 Procitovano 12 veresnya 2017 Div takozh red Hromosoma 21 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title ERG amp oldid 39970318