PSMA7 angl Proteasome subunit alpha 7 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 20 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 248 aminokislot a molekulyarna masa 27 887 5 PSMA7Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB4R3O 4R67 1IRU 5A0QIdentifikatoriSimvoliPSMA7 C6 HSPC RC6 1 XAPC7 HEL S 276 proteasome subunit alpha 7 proteasome 20S subunit alpha 7Zovnishni ID OMIM 606607 MGI 1347070 HomoloGene 105299 GeneCards PSMA7Reaguye na spolukuKarfilzomib ixazomib Oprozomib 1 Ontologiya genaMolekulyarna funkciya endopeptidase activity GO 0070122 peptidase activity GO 0001948 GO 0016582 protein binding identical protein binding threonine type endopeptidase activity hydrolase activityKlitinna komponenta citoplazma gialoplazma Nukleoplazma Proteasoma ekzosoma klitinne yadro proteasome core complex postsynapse proteasome core complex alpha subunit complexBiologichnij proces regulation of cellular amino acid metabolic process antigen processing and presentation of exogenous peptide antigen via MHC class I TAP dependent ubiquitin dependent protein catabolic process regulation of mRNA stability positive regulation of canonical Wnt signaling pathway protein polyubiquitination stimulatory C type lectin receptor signaling pathway tumor necrosis factor mediated signaling pathway proteoliz MAPK cascade Fc epsilon receptor signaling pathway NIK NF kappaB signaling anaphase promoting complex dependent catabolic process proteolysis involved in cellular protein catabolic process T cell receptor signaling pathway negative regulation of canonical Wnt signaling pathway proteasome mediated ubiquitin dependent protein catabolic process GO 0022415 viral process Wnt signaling pathway planar cell polarity pathway negative regulation of G2 M transition of mitotic cell cycle protein deubiquitination SCF dependent proteasomal ubiquitin dependent protein catabolic process transmembrannij transport regulation of transcription from RNA polymerase II promoter in response to hypoxia posttranslyacijna modifikaciya regulation of hematopoietic stem cell differentiation proteasomal protein catabolic process proteasomal ubiquitin independent protein catabolic process interleukin 1 mediated signaling pathway regulation of mitotic cell cycle phase transitionDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez5688 26444Ensembl ENSG00000101182 ENSMUSG00000027566UniProt O14818 Q9Z2U0RefSeq mRNK NM 152255NM 002792NM 001289476NM 011969RefSeq bilok NP 002783NP 001276405NP 036099Lokus UCSC Hr 20 62 14 62 14 MbHr 2 179 68 179 68 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKKKQKKASA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do gidrolaz proteaz treoninovih proteaz Zadiyanij u takomu biologichnomu procesi yak vzayemodiya hazyayin virus Lokalizovanij u citoplazmi yadri Literatura red The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Yano M Koumoto Y Kanesaki Y Wu X Kido H 2004 20S proteasome prevents aggregation of heat denatured proteins without PA700 regulatory subcomplex like a molecular chaperone Biomacromolecules 5 1465 1469 PubMed DOI 10 1021 bm049957a Hillman R T Green R E Brenner S E 2004 An unappreciated role for RNA surveillance Genome Biol 5 R8 1 R8 16 PubMed DOI 10 1186 gb 2004 5 2 r8 Dong J Chen W Welford A Wandinger Ness A 2004 The proteasome alpha subunit XAPC7 interacts specifically with Rab7 and late endosomes J Biol Chem 279 21334 21342 PubMed DOI 10 1074 jbc M401022200 Rut W Drag M 2016 Human 20S proteasome activity towards fluorogenic peptides of various chain lengths Biol Chem 397 921 926 PubMed DOI 10 1515 hsz 2016 0176 da Fonseca P C Morris E P 2015 Cryo EM reveals the conformation of a substrate analogue in the human 20S proteasome core Nat Commun 6 7573 7573 PubMed DOI 10 1038 ncomms8573Primitki red Spoluki yaki fizichno vzayemodiyut z Proteasome 20S subunit alpha 7 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 9536 angl Procitovano 21 serpnya 2017 UniProt O14818 angl Arhiv originalu za 10 serpnya 2017 Procitovano 21 serpnya 2017 Div takozh red Hromosoma 20 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title PSMA7 amp oldid 38321972
