HRH2 angl Histamine receptor H2 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 5 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 359 aminokislot a molekulyarna masa 40 098 5 HRH2IdentifikatoriSimvoliHRH2 H2R histamine receptor H2 HH2RZovnishni ID OMIM 142703 MGI 108482 HomoloGene 40613 GeneCards HRH2Reaguye na spolukuamthamine impromidine Cimetidin ciproxifan clobenpropit conessine MK 0249 pitolisant E ranitidine ABT 239 1 Ontologiya genaMolekulyarna funkciya G protein coupled receptor activity signal transducer activity histamine receptor activity G protein coupled serotonin receptor activity neurotransmitter receptor activityKlitinna komponenta integral component of membrane membrana klitinna membrana integral component of plasma membrane Dendrit nejrobiologiya Biologichnij proces visual learning epithelial cell morphogenesis gastric acid secretion G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger pam yat toxin transport regulation of synaptic plasticity gastrin induced gastric acid secretion positive regulation of vasoconstriction GO 0046730 GO 0046737 GO 0046738 GO 0046736 Imunna vidpovid digestive tract development GO 0072468 Signalna transdukciya gland development histamine induced gastric acid secretion G protein coupled receptor signaling pathway chemical synaptic transmission G protein coupled serotonin receptor signaling pathwayDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez3274 15466Ensembl ENSG00000113749 ENSMUSG00000034987UniProt P25021 P97292RefSeq mRNK NM 001131055NM 022304NM 001367711NM 001393460NM 001393461NM 001010973NM 008286RefSeq bilok NP 001124527NP 001354640NP 001010973Lokus UCSC Hr 5 175 66 175 71 MbHr 13 54 35 54 39 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDRA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do receptoriv g bilokspryazhenih receptoriv bilkiv vnutrishnoklitinnogo signalingu Zadiyanij u takih biologichnih procesah yak polimorfizm alternativnij splajsing Lokalizovanij u klitinnij membrani membrani Div takozh RedaguvatiHromosoma 5Primitki Redaguvati Spoluki yaki fizichno vzayemodiyut z HRH2 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 5183 angl Arhiv originalu za 13 chervnya 2017 Procitovano 31 serpnya 2017 UniProt P25021 angl Arhiv originalu za 26 serpnya 2017 Procitovano 31 serpnya 2017 Literatura RedaguvatiNishi T Koike T Oka T Maeda M Futai M 1995 Identification of the promoter region of the human histamine H2 receptor gene Biochem Biophys Res Commun 210 616 623 PubMed DOI 10 1006 bbrc 1995 1703 Kitano T Liu Y H Ueda S Saitou N 2004 Human specific amino acid changes found in 103 protein coding genes Mol Biol Evol 21 936 944 PubMed DOI 10 1093 molbev msh100 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Orange P R Heath P R Wright S R Pearson R C A 1996 Allelic variations of the human histamine H2 receptor gene NeuroReport 7 1293 1296 PubMed DelValle J Gantz I 1997 Novel insights into histamine H2 receptor biology Am J Physiol 273 G987 G996 PubMed nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title HRH2 amp oldid 38797229
