GPD1L angl Glycerol 3 phosphate dehydrogenase 1 like bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 3 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 351 aminokislot a molekulyarna masa 38 419 5 GPD1LNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB2PLAIdentifikatoriSimvoliGPD1L GPD1 L glycerol 3 phosphate dehydrogenase 1 like glycerol 3 phosphate dehydrogenase 1 likeZovnishni ID OMIM 611778 MGI 1289257 HomoloGene 56097 GeneCards GPD1LPov yazani genetichni zahvoryuvannyaBrugada syndrome 2 1 Ontologiya genaMolekulyarna funkciya GO 0050229 oxidoreductase activity acting on the CH OH group of donors NAD or NADP as acceptor sodium channel regulator activity protein homodimerization activity transmembrane transporter binding NAD binding oxidoreductase activity glycerol 3 phosphate dehydrogenase NAD activity Klitinna komponenta citoplazma gialoplazma membrana klitinna membrana glycerol 3 phosphate dehydrogenase complex ekzosomaBiologichnij proces phosphatidic acid biosynthetic process regulation of ventricular cardiac muscle cell membrane depolarization negative regulation of protein kinase C signaling glycerol 3 phosphate catabolic process ventricular cardiac muscle cell action potential glycerol 3 phosphate metabolic process NAD metabolic process regulation of heart rate NADH metabolic process regulation of sodium ion transmembrane transporter activity positive regulation of protein localization to cell surface GO 0061423 positive regulation of sodium ion transport negative regulation of peptidyl serine phosphorylation carbohydrate metabolic process potencial diyi NADH oxidationDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez23171 333433Ensembl ENSG00000152642 ENSMUSG00000050627UniProt Q8N335 Q3ULJ0RefSeq mRNK NM 015141NM 175380RefSeq bilok NP 055956NP 780589Lokus UCSC Hr 3 32 11 32 17 MbHr 9 114 73 114 76 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHTA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do oksidoreduktaz fosfoproteyiniv Zadiyanij u takomu biologichnomu procesi yak polimorfizm Bilok maye sajt dlya zv yazuvannya z NAD Lokalizovanij u citoplazmi Literatura red The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Valdivia C R Ueda K Ackerman M J Makielski J C 2009 GPD1L links redox state to cardiac excitability by PKC dependent phosphorylation of the sodium channel SCN5A Am J Physiol 297 H1446 H1452 PubMed DOI 10 1152 ajpheart 00513 2009Primitki red Zahvoryuvannya genetichno pov yazani z GPD1L pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 28956 angl Procitovano 30 serpnya 2017 UniProt Q8N335 angl Arhiv originalu za 26 zhovtnya 2017 Procitovano 30 serpnya 2017 Div takozh red Hromosoma 3 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Na cyu stattyu ne posilayutsya inshi statti Vikipediyi Bud laska skoristajtesya pidkazkoyu ta rozstavte posilannya vidpovidno do prijnyatih rekomendacij Otrimano z https uk wikipedia org w index php title GPD1L amp oldid 35618551
