MS4A1 angl Membrane spanning 4 domains A1 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 11 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 297 aminokislot a molekulyarna masa 33 077 5 MS4A1Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB3PP4 2OSL 3BKYIdentifikatoriSimvoliMS4A1 B1 Bp35 CD20 CVID5 LEU 16 MS4A2 S7 membrane spanning 4 domains A1 FMC7Zovnishni ID OMIM 112210 MGI 88321 HomoloGene 7259 GeneCards MS4A1Reaguye na spolukuOkrelizumab 1 Ontologiya genaMolekulyarna funkciya epidermal growth factor receptor binding GO 0001948 GO 0016582 protein binding MHC class II protein complex bindingKlitinna komponenta integral component of membrane klitinna membrana integral component of plasma membrane ekzosoma membrana external side of plasma membrane extracellular space klitinne yadroBiologichnij proces B cell activation B cell proliferation humoral immune response response to bacteriumDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez931 12482Ensembl ENSG00000156738 ENSMUSG00000024673UniProt P11836 P19437RefSeq mRNK NM 152866NM 021950NM 152867NM 007641RefSeq bilok NP 068769NP 690605NP 690606NP 031667Lokus UCSC Hr 11 60 46 60 47 MbHr 19 11 23 11 24 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSPA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do fosfoproteyiniv Zadiyanij u takomu biologichnomu procesi yak alternativnij splajsing Lokalizovanij u klitinnij membrani membrani Literatura RedaguvatiStamenkovic I Seed B 1988 Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 B1 Bp35 a type III integral membrane protein J Exp Med 167 1975 1980 PubMed DOI 10 1084 jem 167 6 1975 Tedder T F Streuli M Schlossman S F Saito H 1988 Isolation and structure of a cDNA encoding the B1 CD20 cell surface antigen of human B lymphocytes Proc Natl Acad Sci U S A 85 208 212 PubMed DOI 10 1073 pnas 85 1 208 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Carrascal M Ovelleiro D Casas V Gay M Abian J 2008 Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment J Proteome Res 7 5167 5176 PubMed DOI 10 1021 pr800500r Einfeld D A Brown J P Valentine M A Clark E A Ledbetter J A 1988 Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains EMBO J 7 711 717 PubMed Tedder T F Klejman G Schlossman S F Saito H 1989 Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 B1 J Immunol 142 2560 2568 PubMedPrimitki Redaguvati Spoluki yaki fizichno vzayemodiyut z MS4A1 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 7315 angl Procitovano 8 veresnya 2017 UniProt P11836 angl Arhiv originalu za 24 lipnya 2014 Procitovano 8 veresnya 2017 Div takozh RedaguvatiHromosoma 11 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title MS4A1 amp oldid 35661326
