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Enolaza 1 angl Enolase 1 bilok yakij koduyetsya genom ENO1 roztashovanim u lyudej na korotkomu plechi 1 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 434 aminokislot a molekulyarna masa 47 169 4 Enolaza 1Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB2PSN 3B97IdentifikatoriSimvoliENO1 ENO1L1 MPB1 NNE PPH HEL S 17 enolase 1Zovnishni ID OMIM 172430 MGI 95393 HomoloGene 134343 GeneCards ENO1Ontologiya genaMolekulyarna funkciya DNA binding zv yazuvannya z ionom metalu GO 0001948 GO 0016582 protein binding lyase activity GTPase binding magnesium ion binding RNA binding cadherin binding GO 0001078 GO 0001214 GO 0001206 DNA binding transcription repressor activity RNA polymerase II specific phosphopyruvate hydratase activity protein homodimerization activity RNA polymerase II transcription regulatory region sequence specific DNA bindingKlitinna komponenta citoplazma M band membrana ekzosoma klitinne yadro extracellular space phosphopyruvate hydratase complex gialoplazma klitinna membrana cell surface cell cortex regionBiologichnij proces Glyukoneogenez GO 0009373 regulation of transcription DNA templated glikoliz response to virus transcription DNA templated negative regulation of cell growth GO 0045996 negative regulation of transcription DNA templated GO 1901227 negative regulation of transcription by RNA polymerase II positive regulation of plasminogen activation positive regulation of muscle contraction canonical glycolysis negative regulation of hypoxia induced intrinsic apoptotic signaling pathway positive regulation of ATP biosynthetic processDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez2023 13806Ensembl ENSG00000074800 ENSMUSG00000063524UniProt P06733 P17182RefSeq mRNK NM 001201483NM 001428NM 001353346NM 023119NM 001379127NM 001379128RefSeq bilok NP 001188412NP 001419NP 001340275NP 001366056NP 001366057NP 075608NP 001020559Lokus UCSC Hr 1 8 86 8 88 MbHr 4 150 32 150 33 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAKA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Cej bilok za funkciyami nalezhit do represoriv liaz Zadiyanij u takih biologichnih procesah yak glikoliz transkripciya regulyaciya transkripciyi aktivaciya plazminogenu Bilok maye sajt dlya zv yazuvannya z ionami metaliv DNK ionom magniyu Lokalizovanij u klitinnij membrani citoplazmi yadri membrani Literatura red Giallongo A Feo S Moore R Croce C M Showe L C 1986 Molecular cloning and nucleotide sequence of a full length cDNA for human alpha enolase Proc Natl Acad Sci U S A 83 6741 6745 PubMed DOI 10 1073 pnas 83 18 6741 Ray R Miller D M 1991 Cloning and characterization of a human c myc promoter binding protein Mol Cell Biol 11 2154 2161 PubMed DOI 10 1128 MCB 11 4 2154 Walter M Berg H Leidenberger F A Schweppe K W Northemann W 1995 Autoreactive epitopes within the human alpha enolase and their recognition by sera from patients with endometriosis J Autoimmun 8 931 945 PubMed DOI 10 1016 S0896 8411 95 80027 1 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Onyango P Lubyova B Gardellin P Kurzbauer R Weith A 1998 Molecular cloning and expression analysis of five novel genes in chromosome 1p36 Genomics 50 187 198 PubMed DOI 10 1006 geno 1997 5186 Sugahara T Nakajima H Shirahata S Murakami H 1992 Purification and characterization of immunoglobulin production stimulating factor II beta derived from Namalwa cells Cytotechnology 10 137 146 PubMed DOI 10 1007 BF00570890Primitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 3350 angl Arhiv originalu za 7 chervnya 2016 Procitovano 30 sichnya 2017 UniProt P06733 angl Arhiv originalu za 20 grudnya 2016 Procitovano 30 sichnya 2017 Div takozh red Hromosoma 1 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Enolaza 1 amp oldid 35052153