Alaninaminotransferaza ALT AlAT angl Alanine aminotransferase abo alanintransaminaza angl Alanine transaminase ranishe nazivalasya takozh glutamat piruvat transaminaza angl glutamate pyruvate transaminase angl glutamic pyruvic transaminase abo alanin piruvat transaminaza bilok yakij koduyetsya genom roztashovanim u lyudej na dovgomu plechi 8 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 496 aminokislot a molekulyarna masa 54 637 4 GPTIdentifikatoriSimvoliGPT AAT1 ALT1 GPT1 glutamic pyruvic transaminaseZovnishni ID OMIM 138200 MGI 95802 HomoloGene 134231 GeneCards GPTshifr KF 2 6 1 2Ontologiya genaMolekulyarna funkciya transferase activity L alanine 2 oxoglutarate aminotransferase activity pyridoxal phosphate binding katalitichna aktivnist transaminase activityKlitinna komponenta citoplazma gialoplazma ekzosoma extracellular spaceBiologichnij proces L alanine catabolic process cellular amino acid biosynthetic process BiosintezDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez2875 76282Ensembl ENSG00000167701 ENSMUSG00000022546UniProt P24298 Q8QZR5RefSeq mRNK NM 005309NM 182805RefSeq bilok NP 005300NP 001369593NP 001369594NP 877957Lokus UCSC Hr 8 144 5 144 51 MbHr 15 76 58 76 58 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYSA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Cej bilok za funkciyami nalezhit do transferaz aminotransferaz fosfoproteyiniv Zadiyanij u takomu biologichnomu procesi yak acetilyuvannya Bilok maye sajt dlya zv yazuvannya z piridoksal fosfatom Lokalizovanij u citoplazmi Alaninaminotransferaza sintezuyetsya vnutrishnoklitinno i v normi lishe nevelika kilkist cogo fermentu potraplyaye v krov Pri poshkodzhenni klitin pechinki pri gepatitah cirozi pechinki otruyennyah cej ferment potraplyaye v krov sho viyavlyayut laboratornimi metodami kolorimetrichnij u mmol l god kinetichnij 5 u avtomatichnih ta napivavtomatichnih analizatorah v odinicyah aktivnosti U l MO l Takozh aktivnist ciyeyi aminotransferazi mozhe pidvishuvatisya pri infarkti miokarda ta inshih stanah Zmist 1 Div takozh 2 Primitki 3 Dzherela 4 Literatura 5 PosilannyaDiv takozh RedaguvatiAspartataminotransferaza Hromosoma 8Primitki Redaguvati Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 4552 angl Arhiv originalu za 14 sichnya 2018 Procitovano 12 sichnya 2018 UniProt P24298 angl Arhiv originalu za 25 sichnya 2018 Procitovano 12 sichnya 2018 Bazuyetsya na zalezhnosti shvidkosti himichnoyi reakciyi vid koncentraciyi reaguyuchih rechovin Dzherela RedaguvatiKlinichna laboratorna diagnostika Navch posib dlya med VNZ IV riv akred Za red B D Lucika Medicina 2011 288 stor ISBN 978 617 505 129 0 Literatura RedaguvatiThe status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Yang R Z Blaileanu G Hansen B C Shuldiner A R Gong D W 2002 cDNA cloning genomic structure chromosomal mapping and functional expression of a novel human alanine aminotransferase Genomics 79 445 450 PubMed DOI 10 1006 geno 2002 6722Posilannya RedaguvatiALT MedlinePlus Medical Encyclopedia Arhivovano 30 veresnya 2011 u Wayback Machine Otrimano z https uk wikipedia org w index php title Alaninaminotransferaza amp oldid 40359136
