ZFY angl Zinc finger protein Y linked bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na Y hromosomi 2 Dovzhina polipeptidnogo lancyuga bilka stanovit 801 aminokislot a molekulyarna masa 90 505 3 ZFYNayavni strukturiPDBPoshuk dlya lyudej PDBe RCSBSpisok kodiv PDB1KLR 1KLS 1XRZ 5ZNFIdentifikatoriSimvoliZFY ZNF911 zinc finger protein Y linked zinc finger protein Y linkedZovnishni ID OMIM 490000 HomoloGene 88465 GeneCards ZFYOntologiya genaMolekulyarna funkciya DNA binding zv yazuvannya z ionom metalu nucleic acid binding GO 0001948 GO 0016582 protein binding GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specificKlitinna komponenta klitinne yadro Nukleoplazma YaderceBiologichnij proces multicellular organism development transcription DNA templated GO 0009373 regulation of transcription DNA templated GO 0044324 GO 0003256 GO 1901213 GO 0046019 GO 0046020 GO 1900094 GO 0061216 GO 0060994 GO 1902064 GO 0003258 GO 0072212 regulation of transcription by RNA polymerase IIDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez7544 n dEnsembl ENSG00000067646 n dUniProt P08048 n dRefSeq mRNK NM 001145275NM 001145276NM 003411n dRefSeq bilok NP 001138747NP 001138748NP 003402NP 001356631NP 001356632NP 001356633NP 001356634NP 001356635NP 001356636NP 001356637NP 001356638NP 001356639n dLokus UCSC Hr Y 2 94 2 98 Mbn dPubMed search 1 n dVikidaniDiv Red dlya lyudej Poslidovnist aminokislot1020304050MDEDEFELQPQEPNSFFDGIGADATHMDGDQIVVEIQEAVFVSNIVDSDITVHNFVPDDPDSVVIQDVVEDVVIEEDVQCSDILEEADVSENVIIPEQVLDSDVTEEVSLPHCTVPDDVLASDITSTSMSMPEHVLTSESMHVCDIGHVEHMVHDSVVEAEIITDPLTSDIVSEEVLVADCAPEAVIDASGISVDQQDNDKASCEDYLMISLDDAGKIEHDGSTGVTIDAESEMDPCKVDSTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNSSIRVPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAAAVHEQQIDEDEMKTFVPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKKRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYHCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELRKHMRIHTGEKPYQCQYCEYRSADSSNLKTHIKTKHSKEMPFKCDICLLTFSDTKEVQQHTLVHQESKTHQCLHCDHKSSNSSDLKRHVISVHTKDYPHKCEMCEKGFHRPSELKKHVAVHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLPA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do aktivatoriv fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak transkripciya regulyaciya transkripciyi alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z ionami metaliv ionom cinku DNK Lokalizovanij u yadri Literatura red Palmer M S Berta P Sinclair A H Pym B Goodfellow P N 1990 Comparison of human ZFY and ZFX transcripts Proc Natl Acad Sci U S A 87 1681 1685 PubMed DOI 10 1073 pnas 87 5 1681 Erlandsson R Wilson J F Paabo S 2000 Sex chromosomal transposable element accumulation and male driven substitutional evolution in humans Mol Biol Evol 17 804 812 PubMed DOI 10 1093 oxfordjournals molbev a026359 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Grants J Flanagan E Yee A Romaniuk P J 2010 Characterization of the DNA binding activity of the ZFY zinc finger domain Biochemistry 49 679 686 PubMed DOI 10 1021 bi9018626 Kochoyan M Keutmann H T Weiss M A 1991 Alternating zinc fingers in the human male associated protein ZFY refinement of the NMR structure of an even finger by selective deuterium labeling and implications for DNA recognition Biochemistry 30 7063 7072 PubMed DOI 10 1021 bi00243a005 Lau Y F C Chan K 1989 The putative testis determining factor and related genes are expressed as discrete sized transcripts in adult gonadal and somatic tissues Am J Hum Genet 45 942 952 PubMedPrimitki red Human PubMed Reference HUGO Gene Nomenclature Commitee HGNC 12870 angl Procitovano 13 veresnya 2017 UniProt P08048 angl Arhiv originalu za 11 lyutogo 2017 Procitovano 13 veresnya 2017 Div takozh red Hromosoma Y nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title ZFY amp oldid 35771702
