DNTT angl DNA nucleotidylexotransferase bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 10 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 509 aminokislot a molekulyarna masa 58 536 4 DNTTNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB2COEIdentifikatoriSimvoliDNTT TDT DNA nucleotidylexotransferase Terminal deoxynucleotidyl transferaseZovnishni ID OMIM 187410 MGI 98659 HomoloGene 3014 GeneCards DNTTOntologiya genaMolekulyarna funkciya transferase activity DNA binding DNA directed DNA polymerase activity nucleotidyltransferase activity GO 0001948 GO 0016582 protein binding zv yazuvannya z ionom metalu DNA nucleotidylexotransferase activity DNK polimeraza DNA polymerase activityKlitinna komponenta klitinne yadro Nukleoplazma GO 0035327 Euhromatin nuclear matrix citoplazma gialoplazmaBiologichnij proces DNA metabolic process DNA biosynthetic process DNA modification response to ATP double strand break repair via nonhomologous end joiningDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez1791 21673Ensembl ENSG00000107447 ENSMUSG00000025014UniProt P04053 P09838RefSeq mRNK NM 001017520NM 004088NM 001043228NM 009345RefSeq bilok NP 001017520NP 004079NP 001036693NP 033371Lokus UCSC Hr 10 96 3 96 34 MbHr 19 41 02 41 05 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRQFERDLRRYATHERKMILDNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNAA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do transferaz fosfoproteyiniv Zadiyanij u takomu biologichnomu procesi yak alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z ionami metaliv ionom magniyu Lokalizovanij u yadri Literatura red Riley L K Morrow J K Danton M J Coleman M S 1988 Human terminal deoxyribonucleotidyltransferase molecular cloning and structural analysis of the gene and 5 flanking region Proc Natl Acad Sci U S A 85 2489 2493 PubMed DOI 10 1073 pnas 85 8 2489 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Koiwai O Morita A 1988 Isolation of putative promoter region for human terminal deoxynucleotidyltransferase gene Biochem Biophys Res Commun 154 91 100 PubMed DOI 10 1016 0006 291X 88 90654 7 Peterson R C Cheung L C Mattaliano R J Chang L M S Bollum F J 1984 Molecular cloning of human terminal deoxynucleotidyltransferase Proc Natl Acad Sci U S A 81 4363 4367 PubMed DOI 10 1073 pnas 81 14 4363 Mahajan K N Mitchell B S 2003 Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase Proc Natl Acad Sci U S A 100 10746 10751 PubMed DOI 10 1073 pnas 1631060100 Yang B Gathy K N Coleman M S 1994 Mutational analysis of residues in the nucleotide binding domain of human terminal deoxynucleotidyl transferase J Biol Chem 269 11859 11868 PubMedPrimitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 2983 angl Procitovano 8 veresnya 2017 UniProt P04053 angl Arhiv originalu za 24 veresnya 2017 Procitovano 8 veresnya 2017 Div takozh red Hromosoma 10 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title DNTT amp oldid 35597764
