TCF3 angl Transcription factor 3 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 19 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 654 aminokislot a molekulyarna masa 67 600 5 TCF3Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB2MH0 2YPA 2YPB 3U5VIdentifikatoriSimvoliTCF3 E2A E47 ITF1 TCF 3 VDIR bHLHb21 AGM8 transcription factor 3 p75Zovnishni ID OMIM 147141 MGI 98510 HomoloGene 2408 GeneCards TCF3Pov yazani genetichni zahvoryuvannyalimfogranulomatoz 1 Ontologiya genaMolekulyarna funkciya DNA binding sequence specific DNA binding protein dimerization activity protein homodimerization activity GO 0001131 GO 0001151 GO 0001130 GO 0001204 DNA binding transcription factor activity mitogen activated protein kinase kinase kinase binding vitamin D response element binding GO 0001105 transcription coactivator activity transcription factor binding GO 0000980 RNA polymerase II cis regulatory region sequence specific DNA binding GO 0001078 GO 0001214 GO 0001206 DNA binding transcription repressor activity RNA polymerase II specific bHLH transcription factor binding E box binding GO 0001948 GO 0016582 protein binding protein heterodimerization activity GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specificKlitinna komponenta citoplazma transcription regulator complex RNA polymerase II transcription regulator complex klitinne yadro nuclear speck Nukleoplazma GO 0009327 protein containing complexBiologichnij proces Diferenciaciya klitin GO 0009373 regulation of transcription DNA templated positive regulation of muscle cell differentiation positive regulation of DNA binding transcription factor activity GO 1901227 negative regulation of transcription by RNA polymerase II transcription DNA templated nejrobiologiya rozvitku GO 0060469 GO 0009371 positive regulation of transcription DNA templated regulation of G1 S transition of mitotic cell cycle B cell lineage commitment positive regulation of cell cycle positive regulation of B cell proliferation positive regulation of neuron differentiation B cell differentiation immunoglobulin V D J recombination GO 0003257 GO 0010735 GO 1901228 GO 1900622 GO 1904488 positive regulation of transcription by RNA polymerase II regulation of hematopoietic stem cell differentiationDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez6929 21423Ensembl ENSG00000071564 ENSMUSG00000020167UniProt P15923 P15806RefSeq mRNK NM 001136139NM 003200NM 001351778NM 001351779NM 001164147NM 001164148NM 001164149NM 001164150NM 001164151NM 001164152NM 001164153NM 011548NM 001378903NM 001378904NM 001378905NM 001378908NM 001378910NM 001378912NM 001378913NM 001378914RefSeq bilok NP 001129611NP 003191NP 001338707NP 001338708NP 001157619NP 001157620NP 001157621NP 001157622NP 001157623NP 001157624NP 001157625NP 035678NP 001365832NP 001365833NP 001365834NP 001365837NP 001365839NP 001365841NP 001365842NP 001365843Lokus UCSC Hr 19 1 61 1 65 MbHr 10 80 25 80 27 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHMA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak transkripciya regulyaciya transkripciyi diferenciaciya klitin nejrogenez alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z DNK Lokalizovanij u yadri Literatura red Kamps M P Murre C Sun X H Baltimore D 1990 A new homeobox gene contributes the DNA binding domain of the t 1 19 translocation protein in pre B ALL Cell 60 547 555 PubMed DOI 10 1016 0092 8674 90 90658 2 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Murre C McCaw P S Baltimore D 1989 A new DNA binding and dimerization motif in immunoglobulin enhancer binding daughterless MyoD and myc proteins Cell 56 777 783 PubMed DOI 10 1016 0092 8674 89 90682 X Henthorn P McCarrick Walmsley R Kadesch T 1990 Sequence of the cDNA encoding ITF 1 a positive acting transcription factor Nucleic Acids Res 18 677 677 PubMed DOI 10 1093 nar 18 3 677 Zhang Y Bina M 1991 Sequence of a HeLa cDNA provides the DNA binding domain and carboxy terminus of HE47 a human helix loop helix protein related to the enhancer binding factor E47 DNA Seq 2 197 202 PubMed DOI 10 3109 10425179109039690 Henthorn P Kiledjian M Kadesch T 1990 Two distinct transcription factors that bind the immunoglobulin enhancer microE5 kappa 2 motif Science 247 467 470 PubMed DOI 10 1126 science 2105528Primitki red Zahvoryuvannya genetichno pov yazani z TCF3 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 11633 angl Procitovano 12 veresnya 2017 UniProt P15923 angl Arhiv originalu za 11 veresnya 2017 Procitovano 12 veresnya 2017 Div takozh red Hromosoma 19 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title TCF3 amp oldid 35741099
