TBP angl TATA box binding protein bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 6 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 339 aminokislot a molekulyarna masa 37 698 5 TBPNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1TGH 1C9B 1JFI 1NVP 4ROC 4ROE 4ROD 5IY9 5IYA 5FUR 5IYC 5IYB 5IY7 5IY8 5IYD 5IY6IdentifikatoriSimvoliTBP GTF2D GTF2D1 HDL4 SCA17 TFIID TATA box binding protein TATA binding protein TBP1Zovnishni ID OMIM 600075 MGI 101838 HomoloGene 2404 GeneCards TBPPov yazani genetichni zahvoryuvannyaspinocerebellar ataxia type 17 1 Ontologiya genaMolekulyarna funkciya DNA binding GO 0001131 GO 0001151 GO 0001130 GO 0001204 DNA binding transcription factor activity transcription factor binding GO 0000980 RNA polymerase II cis regulatory region sequence specific DNA binding GO 0001948 GO 0016582 protein binding enzyme binding TFIIB class transcription factor binding aryl hydrocarbon receptor binding GO 0001158 cis regulatory region sequence specific DNA binding GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specific RNA polymerase III general transcription initiation factor activity GO 0000983 RNA polymerase II general transcription initiation factor activity RNA polymerase II core promoter sequence specific DNA binding RNA polymerase III transcription regulatory region sequence specific DNA bindingKlitinna komponenta citoplazma transcription factor TFIID complex male pronucleus female pronucleus Nukleoplazma transcription factor TFIIA complex Pronukleus klitinne yadro transcription preinitiation complex GO 0009327 protein containing complex transcription factor TFIIIB complex transcription regulator complexBiologichnij proces termination of RNA polymerase I transcription epigenetic maintenance of chromatin in transcription competent conformation GO 0009373 regulation of transcription DNA templated transcription initiation from RNA polymerase I promoter transcription DNA templated GO 0060469 GO 0009371 positive regulation of transcription DNA templated Spermatogenez DNA templated transcription initiation transcription initiation from RNA polymerase II promoter snRNA transcription by RNA polymerase II regulation of signal transduction by p53 class mediator GO 0022415 viral process regulation of transcription by RNA polymerase III transcription by RNA polymerase II transcription by RNA polymerase III RNA polymerase II preinitiation complex assembly GO 0044324 GO 0003256 GO 1901213 GO 0046019 GO 0046020 GO 1900094 GO 0061216 GO 0060994 GO 1902064 GO 0003258 GO 0072212 regulation of transcription by RNA polymerase II RNA polymerase III preinitiation complex assembly GO 0001183 transcription elongation from RNA polymerase I promoterDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez6908 21374Ensembl ENSG00000112592 ENSMUSG00000014767UniProt P20226 P29037RefSeq mRNK NM 003194NM 001172085NM 013684RefSeq bilok NP 001165556NP 003185NP 038712Lokus UCSC Hr 6 170 55 170 57 MbHr 17 15 72 15 75 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTTA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin Y Tirozin Zadiyanij u takih biologichnih procesah yak vzayemodiya hazyayin virus transkripciya regulyaciya transkripciyi alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z DNK Lokalizovanij u yadri Literatura RedaguvatiPeterson M G Tanese N Pugh B F Tjian R 1990 Functional domains and upstream activation properties of cloned human TATA binding protein Science 248 1625 1630 PubMed DOI 10 1126 science 2363050 Geisberg J V Lee W S Berk A J Ricciardi R P 1994 The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein Proc Natl Acad Sci U S A 91 2488 2492 PubMed DOI 10 1073 pnas 91 7 2488 Veschambre P Simard P Jalinot P 1995 Evidence for functional interaction between the HIV 1 Tat transactivator and the TATA box binding protein in vivo J Mol Biol 250 169 180 PubMed DOI 10 1006 jmbi 1995 0368 LeRoy G Orphanides G Lane W S Reinberg D 1998 Requirement of RSF and FACT for transcription of chromatin templates in vitro Science 282 1900 1904 PubMed DOI 10 1126 science 282 5395 1900 Yuan C X Gurley W B 2000 Potential targets for HSF1 within the preinitiation complex Cell Stress Chaperones 5 229 242 PubMed DOI 10 1379 1466 1268 2000 005 lt 0229 PTFHWT gt 2 0 CO 2 Friedrich J K Panov K I Cabart P Russell J Zomerdijk J C B M 2005 TBP TAF complex SL1 directs RNA polymerase I pre initiation complex formation and stabilizes upstream binding factor at the rDNA promoter J Biol Chem 280 29551 29558 PubMed DOI 10 1074 jbc M501595200Primitki Redaguvati Zahvoryuvannya genetichno pov yazani z TBP pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 11588 angl Procitovano 6 veresnya 2017 UniProt P20226 angl Arhiv originalu za 17 veresnya 2017 Procitovano 6 veresnya 2017 Div takozh RedaguvatiHromosoma 6 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title TBP amp oldid 35740902
