KCNK2 angl Potassium two pore domain channel subfamily K member 2 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 1 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 426 aminokislot a molekulyarna masa 47 093 5 KCNK2Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB4TWKIdentifikatoriSimvoliKCNK2 K2p2 1 TPKC1 TREK TREK 1 TREK1 hTREK 1c hTREK 1e potassium two pore domain channel subfamily K member 2Zovnishni ID OMIM 603219 MGI 109366 HomoloGene 7794 GeneCards KCNK2Reaguye na spolukuArahidonova kislota halothane Riluzol 1 Ontologiya genaMolekulyarna funkciya potassium channel activity voltage gated potassium channel activity potassium channel inhibitor activity outward rectifier potassium channel activity potassium ion leak channel activityKlitinna komponenta axon terminus integral component of membrane endoplasmic reticulum membrane membrana voltage gated potassium channel complex klitinna membrana astrocyte projection calyx of Held cell surface Akson neuronal cell body apical plasma membrane endoplazmatichnij retikulum neuron projection klitinne yadro integral component of plasma membraneBiologichnij proces cochlea development G protein coupled receptor signaling pathway positive regulation of cell death positive regulation of cellular response to hypoxia regulation of membrane potential cardiac ventricle development response to mechanical stimulus pam yat ion transport potassium ion transport response to axon injury potassium ion transmembrane transport negative regulation of cardiac muscle cell proliferation cellular response to hypoxia negative regulation of DNA biosynthetic process stabilization of membrane potentialDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez3776 16526Ensembl ENSG00000082482 ENSMUSG00000037624UniProt O95069 P97438RefSeq mRNK NM 001017424NM 001017425NM 014217NM 001159850NM 001281847NM 001281848NM 010607NM 001357119RefSeq bilok NP 001017424NP 001017425NP 055032NP 001153322NP 001268776NP 001268777NP 034737NP 001344048NP 001389703NP 001389704NP 001389705NP 001389755NP 001389756Lokus UCSC Hr 1 215 01 215 24 MbHr 1 188 94 189 13 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIKA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do ionnih kanaliv fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak transport ioniv transport transport kaliyu Bilok maye sajt dlya zv yazuvannya z kaliyu Lokalizovanij u klitinnij membrani membrani endoplazmatichnomu retikulumi Literatura red The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Plant L D Zuniga L Araki D Marks J D Goldstein S A 2012 SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons Sci Signal 5 RA84 RA84 PubMed DOI 10 1126 scisignal 2003431 Bockenhauer D Zilberberg N Goldstein S A 2001 KCNK2 reversible conversion of a hippocampal potassium leak into a voltage dependent channel Nat Neurosci 4 486 491 PubMedPrimitki red Spoluki yaki fizichno vzayemodiyut z Potassium two pore domain channel subfamily K member 2 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 6277 angl Arhiv originalu za 28 travnya 2017 Procitovano 25 serpnya 2017 UniProt O95069 angl Arhiv originalu za 25 veresnya 2017 Procitovano 25 serpnya 2017 Div takozh red Hromosoma 1 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title KCNK2 amp oldid 35513336
