Interlejkin 5 IL5 angl Interleukin 5 bilok yakij koduyetsya genom IL5 roztashovanim u lyudej na korotkomu plechi 5 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 134 aminokislot a molekulyarna masa 15 238 4 IL5Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB3VA2 1HUL 3QT2IdentifikatoriSimvoliIL5 EDF IL 5 TRF interleukin 5Zovnishni ID OMIM 147850 MGI 96557 HomoloGene 679 GeneCards IL5Ontologiya genaMolekulyarna funkciya interleukin 5 receptor binding GO 0001948 GO 0016582 protein binding growth factor activity protein tyrosine kinase activity cytokine activityKlitinna komponenta extracellular region vnutrishnoklitinnij extracellular spaceBiologichnij proces positive regulation of DNA binding transcription factor activity positive regulation of podosome assembly MAPK cascade GO 0060469 GO 0009371 positive regulation of transcription DNA templated GO 0046730 GO 0046737 GO 0046738 GO 0046736 Imunna vidpovid positive regulation of cell population proliferation positive regulation of eosinophil differentiation positive regulation of peptidyl tyrosine phosphorylation inflammatory response positive regulation of receptor signaling pathway via JAK STAT peptidyl tyrosine phosphorylation positive regulation of B cell proliferation regulation of signaling receptor activity cytokine mediated signaling pathwayDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez3567 16191Ensembl ENSG00000113525 ENSMUSG00000036117UniProt P05113 P04401RefSeq mRNK NM 000879NM 010558RefSeq bilok NP 000870NP 034688Lokus UCSC Hr 5 132 54 132 56 MbHr 11 53 61 53 62 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIESA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do citokiniv faktoriv rostu Sekretovanij nazovni Literatura red The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Proudfoot A E I Davies J G Turcatti G Wingfield P T 1991 Human interleukin 5 expressed in Escherichia coli assignment of the disulfide bridges of the purified unglycosylated protein FEBS Lett 283 61 64 PubMed DOI 10 1016 0014 5793 91 80553 F Tanabe T Konishi M Mizuta T Noma T Honjo T 1987 Molecular cloning and structure of the human interleukin 5 gene J Biol Chem 262 16580 16584 PubMedPrimitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 6016 angl Arhiv originalu za 4 veresnya 2017 Procitovano 31 serpnya 2017 UniProt P05113 angl Arhiv originalu za 4 veresnya 2017 Procitovano 31 serpnya 2017 Div takozh red Hromosoma 5 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Interlejkin 5 amp oldid 35810698
