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GHSR angl Growth hormone secretagogue receptor bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 3 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 366 aminokislot a molekulyarna masa 41 329 5 GHSRIdentifikatoriSimvoliGHSR GHDP growth hormone secretagogue receptor gene growth hormone secretagogue receptorZovnishni ID OMIM 601898 MGI 2441906 HomoloGene 57161 GeneCards GHSRReaguye na spolukuexamorelin macimorelin anamorelin ulimorelin PF 05190457 1 Ontologiya genaMolekulyarna funkciya hormone binding signal transducer activity peptide hormone binding growth hormone releasing hormone receptor activity growth hormone secretagogue receptor activity G protein coupled receptor activityKlitinna komponenta integral component of membrane membrana cell surface neuron projection membrane raft klitinna membrana Schaffer collateral CA1 synapse postsynapse glutamatergic synapse integral component of synaptic membraneBiologichnij proces negative regulation of interleukin 1 beta production negative regulation of insulin secretion regulation of synapse assembly regulation of hindgut contraction decidualization positive regulation of insulin like growth factor receptor signaling pathway positive regulation of fatty acid metabolic process hormone mediated signaling pathway positive regulation of multicellular organism growth cellular response to insulin stimulus response to food response to hormone actin polymerization or depolymerization negative regulation of inflammatory response GO 0072468 Signalna transdukciya positive regulation of appetite growth hormone secretion adult feeding behavior response to growth hormone positive regulation of eating behavior Spermatogenez female pregnancy learning or memory negative regulation of norepinephrine secretion negative regulation of appetite response to follicle stimulating hormone response to estradiol ghrelin secretion regulation of transmission of nerve impulse regulation of growth hormone secretion cellular response to lipopolysaccharide response to dexamethasone negative regulation of locomotion involved in locomotory behavior cellular response to thyroid hormone stimulus positive regulation of sprouting angiogenesis response to monosodium glutamate regulation of gastric motility positive regulation of vascular endothelial cell proliferation cellular response to insulin like growth factor stimulus negative regulation of macrophage apoptotic process positive regulation of growth regulation of feeding behavior positive regulation of small intestinal transit positive regulation of small intestine smooth muscle contraction G protein coupled receptor signaling pathway regulation of neurotransmitter receptor localization to postsynaptic specialization membrane postsynaptic modulation of chemical synaptic transmission regulation of postsynapse organizationDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez2693 208188Ensembl ENSG00000121853 ENSMUSG00000051136UniProt Q92847 Q99P50RefSeq mRNK NM 198407NM 004122NM 177330RefSeq bilok NP 004113NP 940799NP 796304Lokus UCSC Hr 3 172 44 172 45 MbHr 3 27 43 27 43 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINTA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do receptoriv g bilokspryazhenih receptoriv bilkiv vnutrishnoklitinnogo signalingu Zadiyanij u takih biologichnih procesah yak polimorfizm alternativnij splajsing Lokalizovanij u klitinnij membrani membrani Literatura RedaguvatiPetersenn S Rasch A C Penshorn M Beil F U Schulte H M 2001 Genomic structure and transcriptional regulation of the human growth hormone secretagogue receptor Endocrinology 142 2649 2659 PubMed DOI 10 1210 endo 142 6 8184 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504Primitki Redaguvati Spoluki yaki fizichno vzayemodiyut z growth hormone secretagogue receptor pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 4267 angl Arhiv originalu za 10 veresnya 2015 Procitovano 30 serpnya 2017 UniProt Q92847 angl Arhiv originalu za 6 veresnya 2017 Procitovano 30 serpnya 2017 Div takozh RedaguvatiHromosoma 3 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title GHSR amp oldid 35617355