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FCAR angl Fc fragment of IgA receptor bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 19 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 287 aminokislot a molekulyarna masa 32 265 4 FCARNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1OVZ 1OW0 1UCTIdentifikatoriSimvoliFCAR CD89 CTB 61M7 2 FcalphaRI Fc fragment of IgA receptor Fc alpha receptor FcalphaRZovnishni ID OMIM 147045 HomoloGene 48064 GeneCards FCAROntologiya genaMolekulyarna funkciya IgA receptor activity IgA bindingKlitinna komponenta integral component of membrane extracellular region klitinna membrana integral component of plasma membrane membrana specific granule membrane tertiary granule membrane ficolin 1 rich granule membraneBiologichnij proces GO 0046730 GO 0046737 GO 0046738 GO 0046736 Imunna vidpovid neutrophil degranulation neutrophil mediated immunity positive regulation of neutrophil apoptotic process cellular response to interferon alpha Fc receptor signaling pathway neutrophil activation cellular response to lipopolysaccharide cellular response to interferon gamma cellular response to interleukin 6 cellular response to tumor necrosis factor cellular response to granulocyte macrophage colony stimulating factor stimulus positive regulation of oxidative stress induced cell deathDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez2204 365183Ensembl ENSG00000275564ENSG00000284004ENSG00000273738ENSG00000283953ENSG00000276985ENSG00000275970ENSG00000284061ENSG00000283750ENSG00000278415ENSG00000186431ENSG00000275136ENSG00000276858ENSG00000284245ENSG00000275269ENSG00000274580 n dUniProt P24071 D3ZRL6RefSeq mRNK NM 002000NM 133269NM 133271NM 133272NM 133273NM 133274NM 133277NM 133278NM 133279NM 133280NM 201992RefSeq bilok NP 001991NP 579803NP 579805NP 579806NP 579807NP 579808NP 579811NP 579812NP 973721Lokus UCSC Hr 19 54 87 54 89 Mbn dPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCKA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do receptoriv Zadiyanij u takomu biologichnomu procesi yak alternativnij splajsing Lokalizovanij u klitinnij membrani membrani Takozh sekretovanij nazovni Literatura red Maliszewski C R March C J Schoenborn M A Gimpel S Shen L 1990 Expression cloning of a human Fc receptor for IgA J Exp Med 172 1665 1672 PubMed DOI 10 1084 jem 172 6 1665 Pleass R J Andrews P D Kerr M A Woof J M 1996 Alternative splicing of the human IgA Fc receptor CD89 in neutrophils and eosinophils Biochem J 318 771 777 PubMed DOI 10 1042 bj3180771 Toyabe S Kuwano Y Takeda K Uchiyama M Abo T 1997 IgA nephropathy specific expression of the IgA Fc receptors CD89 on blood phagocytic cells Clin Exp Immunol 110 226 232 PubMed DOI 10 1111 j 1365 2249 1997 tb08321 x Abi Rached L Dorighi K Norman P J Yawata M Parham P 2007 Episodes of natural selection shaped the interactions of IgA Fc with FcalphaRI and bacterial decoy proteins J Immunol 178 7943 7954 PubMed DOI 10 4049 jimmunol 178 12 7943 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Hillman R T Green R E Brenner S E 2004 An unappreciated role for RNA surveillance Genome Biol 5 R8 1 R8 16 PubMed DOI 10 1186 gb 2004 5 2 r8Primitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 3608 angl Procitovano 12 veresnya 2017 UniProt P24071 angl Arhiv originalu za 23 veresnya 2017 Procitovano 12 veresnya 2017 Div takozh red Hromosoma 19 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title FCAR amp oldid 35437371