CFD angl Complement factor D bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 19 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 253 aminokislot a molekulyarna masa 27 033 5 CFDNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWA 2XWB 4CBN 4CBO 4D9RIdentifikatoriSimvoliCFD ADIPSIN ADN DF PFD complement factor DZovnishni ID OMIM 134350 MGI 87931 HomoloGene 20453 GeneCards CFDPov yazani genetichni zahvoryuvannyarecurrent Neisseria infections due to factor D deficiency 1 Ontologiya genaMolekulyarna funkciya GO 0070122 peptidase activity serine type peptidase activity serine type endopeptidase activity hydrolase activityKlitinna komponenta extracellular region ekzosoma platelet alpha granule lumen secretory granule lumen ficolin 1 rich granule lumen extracellular spaceBiologichnij proces complement activation platelet degranulation complement activation alternative pathway proteoliz immune system process Vrodzhenij imunitet neutrophil degranulation Signalnij shlyah NotchDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez1675 11537Ensembl ENSG00000274619ENSG00000197766 ENSMUSG00000061780UniProt P00746 P03953RefSeq mRNK NM 001928NM 001317335NM 001291915NM 013459NM 001329541RefSeq bilok NP 001304264NP 001919NP 001278844NP 001316470NP 038487Lokus UCSC Hr 19 0 86 0 87 MbHr 10 79 73 79 73 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLAA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do gidrolaz proteaz serinovih proteaz Zadiyanij u takih biologichnih procesah yak imunitet vrodzhenij imunitet alternativnij shlyah aktivaciyi komplementu Sekretovanij nazovni Literatura red The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Niemann M A Bhown A S Bennett J C Volanakis J E 1984 Amino acid sequence of human D of the alternative complement pathway Biochemistry 23 2482 2486 PubMed DOI 10 1021 bi00306a025 Johnson D M A Gagnon J Reid K B M 1984 Amino acid sequence of human factor D of the complement system Similarity in sequence between factor D and proteases of non plasma origin FEBS Lett 166 347 351 PubMed DOI 10 1016 0014 5793 84 80110 6 Volanakis J E Bhown A S Bennett J C Mole J E 1980 Partial amino acid sequence of human factor D homology with serine proteases Proc Natl Acad Sci U S A 77 1116 1119 PubMed DOI 10 1073 pnas 77 2 1116 Davis A E III 1980 Active site amino acid sequence of human factor D Proc Natl Acad Sci U S A 77 4938 4942 PubMed DOI 10 1073 pnas 77 8 4938 Johnson D M A Gagnon J Reid K B M 1980 Factor D of the alternative pathway of human complement Purification alignment and N terminal amino acid sequences of the major cyanogen bromide fragments and localization of the serine residue at the active site Biochem J 187 863 874 PubMed DOI 10 1042 bj1870863Primitki red Zahvoryuvannya genetichno pov yazani z CFD pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 2771 angl Procitovano 21 veresnya 2017 UniProt P00746 angl Arhiv originalu za 11 bereznya 2018 Procitovano 21 veresnya 2017 Div takozh red Hromosoma 19 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title CFD amp oldid 35582800
