ADH1C angl Alcohol dehydrogenase 1C class I gamma polypeptide bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 4 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 375 aminokislot a molekulyarna masa 39 868 4 ADH1CNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1HT0 1U3WIdentifikatoriSimvoliADH1C ADH3 alcohol dehydrogenase 1C class I gamma polypeptideZovnishni ID OMIM 103730 MGI 87921 HomoloGene 73888 GeneCards ADH1COntologiya genaMolekulyarna funkciya oxidoreductase activity zinc ion binding alcohol dehydrogenase NAD activity zv yazuvannya z ionom metalu NAD retinol dehydrogenase activity alcohol dehydrogenase activity zinc dependentKlitinna komponenta citoplazma Nukleoplazma gialoplazma klitinna membranaBiologichnij proces ethanol oxidation retinol metabolic process retinoic acid metabolic processDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez126 11522Ensembl ENSG00000248144 ENSMUSG00000074207UniProt P00326 P00329RefSeq mRNK NM 000669NM 007409RefSeq bilok NP 000660NP 031435Lokus UCSC Hr 4 99 34 99 35 MbHr 3 137 97 138 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTFA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do oksidoreduktaz fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak polimorfizm acetilyaciya Bilok maye sajt dlya zv yazuvannya z NAD ionami metaliv ionom cinku Lokalizovanij u citoplazmi Literatura red Hoeoeg J O Heden L O Larsson K Joernvall H 1986 The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase cDNA structures two amino acid replacements and compatibility with changes in the enzymatic properties Eur J Biochem 159 215 218 PubMed DOI 10 1111 j 1432 1033 1986 tb09855 x Ikuta T Szeto S Yoshida A 1986 Three human alcohol dehydrogenase subunits cDNA structure and molecular and evolutionary divergence Proc Natl Acad Sci U S A 83 634 638 PubMed DOI 10 1073 pnas 83 3 634 Yokoyama S Matsuo Y Rajasekharan S Yokoyama R 1992 Molecular structure of the human alcohol dehydrogenase 3 gene Jpn J Genet 67 167 171 PubMed DOI 10 1266 jjg 67 167 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Niederhut M S Gibbons B J Perez Miller S Hurley T D 2001 Three dimensional structures of the three human class I alcohol dehydrogenases Protein Sci 10 697 706 PubMed DOI 10 1110 ps 45001 Gibbons B J Hurley T D 2004 Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors Biochemistry 43 12555 12562 PubMed DOI 10 1021 bi0489107Primitki red Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 251 angl Arhiv originalu za 23 lipnya 2017 Procitovano 30 serpnya 2017 UniProt P00326 angl Arhiv originalu za 5 veresnya 2017 Procitovano 30 serpnya 2017 Div takozh red Hromosoma 4 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Na cyu stattyu ne posilayutsya inshi statti Vikipediyi Bud laska skoristajtesya pidkazkoyu ta rozstavte posilannya vidpovidno do prijnyatih rekomendacij Otrimano z https uk wikipedia org w index php title ADH1C amp oldid 35334696
