ADH1A angl Alcohol dehydrogenase 1A class I alpha polypeptide bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 4 yi hromosomi 2 Dovzhina polipeptidnogo lancyuga bilka stanovit 375 aminokislot a molekulyarna masa 39 859 3 ADH1ANayavni strukturiPDBPoshuk dlya lyudej PDBe RCSBSpisok kodiv PDB1HSO 1U3TIdentifikatoriSimvoliADH1A ADH1 alcohol dehydrogenase 1A class I alpha polypeptideZovnishni ID OMIM 103700 HomoloGene 88335 GeneCards ADH1Ashifr KF 1 1 1 1Ontologiya genaMolekulyarna funkciya oxidoreductase activity zinc ion binding GO 0001948 GO 0016582 protein binding alcohol dehydrogenase NAD activity zv yazuvannya z ionom metalu alcohol dehydrogenase activity zinc dependent NAD retinol dehydrogenase activityKlitinna komponenta citoplazma Nukleoplazma gialoplazma klitinna membranaBiologichnij proces alcohol metabolic process ethanol oxidation retinol metabolic process retinoic acid metabolic processDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez124 n dEnsembl ENSG00000187758 n dUniProt P07327 n dRefSeq mRNK NM 000667n dRefSeq bilok NP 000658n dLokus UCSC Hr 4 99 28 99 29 Mbn dPubMed search 1 n dVikidaniDiv Red dlya lyudej Poslidovnist aminokislot1020304050MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMFA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do oksidoreduktaz fosfoproteyiniv Zadiyanij u takomu biologichnomu procesi yak acetilyaciya Bilok maye sajt dlya zv yazuvannya z NAD ionami metaliv ionom cinku Lokalizovanij u citoplazmi Literatura red Ikuta T Szeto S Yoshida A 1986 Three human alcohol dehydrogenase subunits cDNA structure and molecular and evolutionary divergence Proc Natl Acad Sci U S A 83 634 638 PubMed DOI 10 1073 pnas 83 3 634 Matsuo Y Yokoyama S 1989 Molecular structure of the human alcohol dehydrogenase 1 gene FEBS Lett 243 57 60 PubMed DOI 10 1016 0014 5793 89 81217 7 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Yasunami M Kikuchi I Sarapata D Yoshida A 1990 The human class I alcohol dehydrogenase gene cluster three genes are tandemly organized in an 80 kb long segment of the genome Genomics 7 152 158 PubMed DOI 10 1016 0888 7543 90 90535 3 Gibbons B J Hurley T D 2004 Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors Biochemistry 43 12555 12562 PubMed DOI 10 1021 bi0489107 Niederhut M S Gibbons B J Perez Miller S Hurley T D 2001 Three dimensional structures of the three human class I alcohol dehydrogenases Protein Sci 10 697 706 PubMed DOI 10 1110 ps 45001Primitki red Human PubMed Reference HUGO Gene Nomenclature Commitee HGNC 249 angl Arhiv originalu za 23 lipnya 2017 Procitovano 30 serpnya 2017 UniProt P07327 angl Arhiv originalu za 29 serpnya 2017 Procitovano 30 serpnya 2017 Div takozh red Hromosoma 4 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Na cyu stattyu ne posilayutsya inshi statti Vikipediyi Bud laska skoristajtesya pidkazkoyu ta rozstavte posilannya vidpovidno do prijnyatih rekomendacij Otrimano z https uk wikipedia org w index php title ADH1A amp oldid 35334691
