TYR angl Tyrosinase bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 11 yi hromosomi 1 Dovzhina polipeptidnogo lancyuga bilka stanovit 529 aminokislot a molekulyarna masa 60 393 2 TirozinazaIdentifikatoriSimvolityrosinasemonophenol oxygenasemonophenol oxidasemonophenolasemonophenoldihydroxy L phenylalanine oxygen oxidoreductasemonophenol monooxidasepolyaromatic oxidasemonophenol L dopa oxygen oxidoreductaseL tyrosine monooxygenasemonophenol dihydroxyphenylalanine oxygen oxidoreductaseN acetyl 6 hydroxytryptophan oxidasetyrosine dopa oxidasepolyphenolaseZovnishni ID GeneCards 1 OrtologiVidi Lyudina MishaEntrezn d n dEnsembl n d n dUniProt n d n dRefSeq mRNK n dn dRefSeq bilok n dn dLokus UCSC n dn dPubMed search n dn dVikidaniDiv Red dlya lyudej Poslidovnist aminokislot1020304050MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHLA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do oksidoreduktaz Zadiyanij u takomu biologichnomu procesi yak alternativnij splajsing Bilok maye sajt dlya zv yazuvannya z ionom midi ionami metaliv Lokalizovanij u membrani Literatura red Giebel L B Strunk K M Spritz R A 1991 Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosinase related segment Genomics 9 435 445 PubMed DOI 10 1016 0888 7543 91 90409 8 Kwon B S Haq A K Pomerantz S H Halaban R 1987 Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c albino locus Proc Natl Acad Sci U S A 84 7473 7477 PubMed DOI 10 1073 pnas 84 21 7473 Bouchard B Fuller B B Vijayasaradhi S Houghton A N 1989 Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA J Exp Med 169 2029 2042 PubMed DOI 10 1084 jem 169 6 2029 Chintamaneni C D Halaban R Kobayashi Y Witkop C J Kwon B S 1991 A single base insertion in the putative transmembrane domain of the tyrosinase gene as a cause for tyrosinase negative oculocutaneous albinism Proc Natl Acad Sci U S A 88 5272 5276 PubMed DOI 10 1073 pnas 88 12 5272 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Takeda A Tomita Y Okinaga S Tagami H Shibahara S 1989 Functional analysis of the cDNA encoding human tyrosinase precursor Biochem Biophys Res Commun 162 984 990 PubMed DOI 10 1016 0006 291X 89 90770 5Primitki red HUGO Gene Nomenclature Commitee HGNC 12442 angl Procitovano 8 veresnya 2017 UniProt P14679 angl Arhiv originalu za 8 veresnya 2017 Procitovano 8 veresnya 2017 Div takozh red Hromosoma 11 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Tirozinaza amp oldid 35085335
