Parvalbumin angl Parvalbumin kalcij zv yazuvalnij bilok sho nalezhit do grupi albuminiv Koduyetsya genom PVALB roztashovanim u lyudini na dovgomu plechi 22 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 110 aminokislot a molekulyarna masa 12 059 5 ParvalbuminNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1RJV 1RK9 s1RK9 1RJVIdentifikatoriSimvoliPVALB D22S749 parvalbuminZovnishni ID OMIM 168890 MGI 97821 HomoloGene 2137 GeneCards PVALBPov yazani genetichni zahvoryuvannyaozhirinnya sexual dysfunction 1 Ontologiya genaMolekulyarna funkciya calcium ion binding protein homodimerization activity zv yazuvannya z ionom metalu protein heterodimerization activityKlitinna komponenta citoplazma Akson neuronal cell body klitinne yadro GO 0009327 protein containing complex stereocilium cuticular plateBiologichnij proces regulation of cytosolic calcium ion concentration cochlea developmentDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez5816 19293Ensembl ENSG00000274665ENSG00000100362 ENSMUSG00000005716UniProt P20472 P32848RefSeq mRNK NM 002854NM 001315532NM 013645NM 001330686RefSeq bilok NP 001302461NP 002845NP 001302461 1NP 002845 1NP 001317615NP 038673Lokus UCSC Hr 22 36 8 36 82 MbHr 15 78 08 78 09 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MSMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAESA Alanin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin Cej bilok zadiyanij u takomu biologichnomu procesi yak acetilyuvannya Parvalbumin maye tri motivi EF hand i strukturno pov yazanij z kalmodulinom i troponinom C z yakim gen parvalbuminu utvoryuye nadrodinu Visoki rivni parvalbuminu sposterigayutsya v m yazah sho shvidko skorochuyutsya nizhchi rivni viyavlyayutsya takozh v mozku i deyakih endokrinnih tkaninah U m yazah parvalbumin obmezhuye riven vilnih ioniv Ca2 sho priskoryuye m yazove rozslablennya Div takozh RedaguvatiHromosoma 22Literatura RedaguvatiBerchtold M W 1989 Parvalbumin genes from human and rat are identical in intron exon organization and contain highly homologous regulatory elements and coding sequences J Mol Biol 210 417 427 PubMed DOI 10 1016 0022 2836 89 90119 8 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Troxler H Kuster T Rhyner J A Gehrig P Heizmann C W 1999 Electrospray ionization mass spectrometry analysis of the Ca2 binding properties of human recombinant alpha parvalbumin and nine mutant proteins Anal Biochem 268 64 71 PubMed DOI 10 1006 abio 1998 3015Primitki Redaguvati Zahvoryuvannya genetichno pov yazani z Parvalbumin pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 9704 angl Procitovano 26 kvitnya 2018 UniProt P20472 angl Procitovano 26 kvitnya 2018 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Parvalbumin amp oldid 32534103
