Kalmodulin 2 angl Calmodulin 1 bilok yakij koduyetsya genom CALM2 roztashovanim u lyudej na korotkomu plechi 19 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 149 aminokislot a molekulyarna masa 16 838 4 CALM2IdentifikatoriSimvoliCALM2 CAMII PHKD PHKD2 LQT15 caM calmodulin 2 phosphorylase kinase delta calmodulin 2 CAMC CAM1 CAMIII CAM3 CALM CALML2Zovnishni ID OMIM 114182 HomoloGene 134804 GeneCards CALM2Pov yazani genetichni zahvoryuvannyasindrom podovzhenogo intervalu QT 1 Ontologiya genaMolekulyarna funkciya calcium ion binding GO 0001948 GO 0016582 protein binding adenylate cyclase binding adenylate cyclase activator activity calcium channel inhibitor activity protein kinase binding protein domain specific binding titin binding N terminal myristoylation domain binding protein serine threonine kinase activator activity transmembrane transporter binding zv yazuvannya z ionom metalu protein phosphatase activator activity disordered domain specific binding nitric oxide synthase regulator activity type 3 metabotropic glutamate receptor binding phosphatidylinositol 3 kinase binding protein N terminus binding calcium dependent protein binding nitric oxide synthase bindingKlitinna komponenta spindle pole klitinne yadro citoplazma centrosoma Centr organizaciyi mikrotrubochok Vereteno podilu Citoskelet spindle microtubule klitinna membrana voltage gated potassium channel complex Sarkomera vezikula GO 0009327 protein containing complex Kalciyevi kanali myelin sheath catalytic complex growth cone synaptic vesicle membrane mitohondrialna membrana neuron projectionBiologichnij proces G2 M transition of mitotic cell cycle regulation of heart rate detection of calcium ion G protein coupled receptor signaling pathway positive regulation of peptidyl threonine phosphorylation negative regulation of peptidyl threonine phosphorylation regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion calcium mediated signaling substantia nigra development positive regulation of protein autophosphorylation regulation of cytokinesis positive regulation of phosphoprotein phosphatase activity positive regulation of protein dephosphorylation positive regulation of DNA binding positive regulation of cyclic nucleotide phosphodiesterase activity response to calcium ion regulation of cardiac muscle contraction negative regulation of ryanodine sensitive calcium release channel activity positive regulation of ryanodine sensitive calcium release channel activity positive regulation of protein serine threonine kinase activity regulation of cell communication by electrical coupling involved in cardiac conduction response to amphetamine activation of adenylate cyclase activity positive regulation of nitric oxide synthase activity response to corticosterone regulation of ryanodine sensitive calcium release channel activity establishment of protein localization to membrane establishment of protein localization to mitochondrial membrane regulation of synaptic vesicle endocytosis regulation of high voltage gated calcium channel activity regulation of synaptic vesicle exocytosisDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez805 n dEnsembl ENSG00000143933 n dUniProt P0DP31P0DP24 n dRefSeq mRNK NM 001305624NM 001305625NM 001305626NM 001743n dRefSeq bilok NP 059022NP 001350598NP 001350599NP 008819NP 001292553NP 001292554NP 001292555NP 001734NP 001316850NP 001316851NP 001316852NP 001316853NP 001316854NP 001316855NP 005175n dLokus UCSC Hr 2 47 16 47 18 Mbn dPubMed search 2 n dVikidaniDiv Red dlya lyudej Poslidovnist aminokislot1020304050MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKA Alanin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin Y Tirozin Kodovanij genom bilok za funkciyeyu nalezhit do fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak polimorfizm acetilyaciya Bilok maye sajt dlya zv yazuvannya z ionami metaliv ionom kalciyu Lokalizovanij u citoplazmi citoskeleti Literatura red Koller M Schnyder B Strehler E E 1990 Structural organization of the human CaMIII calmodulin gene Biochim Biophys Acta 1087 180 189 PubMed DOI 10 1016 0167 4781 90 90203 E The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Kelly S Yotis J Macris M Harley V 2003 Recombinant expression purification and characterisation of the HMG domain of human SRY Protein Pept Lett 10 281 286 PubMed DOI 10 2174 0929866033479004 Spektor A Tsang W Y Khoo D Dynlacht B D 2007 Cep97 and CP110 suppress a cilia assembly program Cell 130 678 690 PubMed DOI 10 1016 j cell 2007 06 027Primitki red Zahvoryuvannya genetichno pov yazani z CALM2 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference HUGO Gene Nomenclature Commitee HGNC 1449 angl Arhiv originalu za 7 veresnya 2017 Procitovano 28 serpnya 2017 UniProt P62158 angl Arhiv originalu za 11 veresnya 2017 Procitovano 28 serpnya 2017 Div takozh red Hromosoma 19 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Kalmodulin 2 amp oldid 38132856
