SOX2 angl SRY box 2 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 3 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 317 aminokislot a molekulyarna masa 34 310 5 SOX2Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1O4X 2LE4IdentifikatoriSimvoliSOX2 ANOP3 MCOPS3 SRY box 2 Sox2 SRY box transcription factor 2Zovnishni ID OMIM 184429 MGI 98364 HomoloGene 68298 GeneCards SOX2Pov yazani genetichni zahvoryuvannyasyndromic microphthalmia 3 1 Ontologiya genaMolekulyarna funkciya DNA binding sequence specific DNA binding miRNA binding GO 0001131 GO 0001151 GO 0001130 GO 0001204 DNA binding transcription factor activity GO 0001077 GO 0001212 GO 0001213 GO 0001211 GO 0001205 DNA binding transcription activator activity RNA polymerase II specific GO 0000975 transcription cis regulatory region binding GO 0001948 GO 0016582 protein binding GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specificKlitinna komponenta citoplazma gialoplazma transcription regulator complex Nukleoplazma klitinne yadroBiologichnij proces rozvitok oka pituitary gland development GO 0009373 regulation of transcription DNA templated negative regulation of neuron differentiation somatic stem cell population maintenance endodermal cell fate specification positive regulation of cell cell adhesion tissue regeneration GO 1901227 negative regulation of transcription by RNA polymerase II GO 0031497 GO 0006336 GO 0034724 GO 0001301 GO 0007580 GO 0034652 GO 0010847 chromatin organization transcription by RNA polymerase II regulation of cysteine type endopeptidase activity involved in apoptotic process adenohypophysis development transcription DNA templated neuronal stem cell population maintenance GO 0060469 GO 0009371 positive regulation of transcription DNA templated multicellular organism development glial cell fate commitment response to wounding osteoblast differentiation positive regulation of cell differentiation negative regulation of epithelial cell proliferation Regulyaciya ekspresiyi geniv inner ear development forebrain development response to growth factor negative regulation of canonical Wnt signaling pathway positive regulation of MAPK cascade GO 0003257 GO 0010735 GO 1901228 GO 1900622 GO 1904488 positive regulation of transcription by RNA polymerase II cytokine mediated signaling pathway Diferenciaciya klitin cell fate commitment central nervous system development neuron differentiationDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez6657 20674Ensembl ENSG00000181449 ENSMUSG00000074637UniProt P48431 P48432RefSeq mRNK NM 003106NM 011443RefSeq bilok NP 003097NP 035573Lokus UCSC Hr 3 181 71 181 71 MbHr 3 34 7 34 71 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSHMA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do aktivatoriv bilkiv rozvitku fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak transkripciya regulyaciya transkripciyi Bilok maye sajt dlya zv yazuvannya z DNK Lokalizovanij u yadri Literatura red Stevanovic M Zuffardi O Collignon J Lovell Badge R Goodfellow P 1994 The cDNA sequence and chromosomal location of the human SOX2 gene Mamm Genome 5 640 642 PubMed DOI 10 1007 BF00411460 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504Primitki red Zahvoryuvannya genetichno pov yazani z SOX2 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 11195 angl Procitovano 30 serpnya 2017 UniProt P48431 angl Arhiv originalu za 30 serpnya 2017 Procitovano 30 serpnya 2017 Div takozh red Hromosoma 3 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title SOX2 amp oldid 35723716
