NCAN angl Neurocan bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 19 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 1 321 aminokislot a molekulyarna masa 143 093 5 NCANIdentifikatoriSimvoliNCAN CSPG3 neurocanZovnishni ID OMIM 600826 MGI 104694 HomoloGene 3229 GeneCards NCANPov yazani genetichni zahvoryuvannyabipolyarnij afektivnij rozlad 1 Ontologiya genaMolekulyarna funkciya calcium ion binding hyaluronic acid binding carbohydrate binding extracellular matrix structural constituentKlitinna komponenta Golgi lumen extracellular region lysosomal lumen GO 0005578 Pozaklitinna matricyaBiologichnij proces chondroitin sulfate catabolic process skeletal system development central nervous system development chondroitin sulfate biosynthetic process extracellular matrix organization dermatan sulfate biosynthetic process adgeziya klitinDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez1463 13004Ensembl ENSG00000130287 ENSMUSG00000002341UniProt O14594 P55066RefSeq mRNK NM 004386NM 007789RefSeq bilok NP 004377NP 031815Lokus UCSC Hr 19 19 21 19 25 MbHr 8 70 55 70 57 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MGAPFVWALGLLMLQMLLFVAGEQGTQDITDASERGLHMQKLGSGSVQAALAELVALPCLFTLQPRPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVRVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAERFDAYCFRAHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTLEEEEVVTPDFQEPLVSSGEEETLILEEKQESQQTLSPTPGDPMLASWPTGEVWLSTVAPSPSDMGAGTAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAVNQMEPPLAMAVTEMLGSGQSRSPWADLTNEVDMPGAGSAGGKSSPEPWLWPPTMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEATVSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSLPLSLTPTGQGGEAMPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGIPGSESGVFDTAESPTSGLQATVDEVQDPWPSVYSKGLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPHPEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPSSTLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPALPGTPMNAGAEEVHSDPCENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVCTKPRRSHRMRRHHHHHQHHHQHHHHKSRKERRKHKKHPTEDWEKDEGNFCA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Zadiyanij u takomu biologichnomu procesi yak klitinna adgeziya Bilok maye sajt dlya zv yazuvannya z ionom kalciyu lektinami Sekretovanij nazovni Literatura red Prange C K Pennacchio L A Lieuallen K Fan W Lennon G G 1998 Characterization of the human neurocan gene CSPG3 Gene 221 199 205 PubMed DOI 10 1016 S0378 1119 98 00455 7 Halim A Ruetschi U Larson G Nilsson J 2013 LC MS MS characterization of O glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins J Proteome Res 12 573 584 PubMed DOI 10 1021 pr300963hPrimitki red Zahvoryuvannya genetichno pov yazani z NCAN pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 2465 angl Procitovano 12 veresnya 2017 UniProt O14594 angl Arhiv originalu za 23 zhovtnya 2017 Procitovano 12 veresnya 2017 Div takozh red Hromosoma 19 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title NCAN amp oldid 35673428
