MSX2 angl Msh homeobox 2 bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 5 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 267 aminokislot a molekulyarna masa 28 897 5 MSX2IdentifikatoriSimvoliMSX2 CRS2 FPP HOX8 MSH PFM PFM1 Msh homeobox 2Zovnishni ID OMIM 123101 MGI 97169 HomoloGene 1837 GeneCards MSX2Pov yazani genetichni zahvoryuvannyaParietal foramina with cleidocranial dysplasia parietal foramina 1 Ontologiya genaMolekulyarna funkciya sequence specific DNA binding DNA binding GO 0001104 transcription coregulator activity GO 0001078 GO 0001214 GO 0001206 DNA binding transcription repressor activity RNA polymerase II specific RNA polymerase II transcription regulatory region sequence specific DNA binding GO 0001948 GO 0016582 protein binding transcription factor binding GO 0001200 GO 0001133 GO 0001201 DNA binding transcription factor activity RNA polymerase II specificKlitinna komponenta klitinne yadro gialoplazma nuclear speckBiologichnij proces negative regulation of cell population proliferation positive regulation of timing of catagen negative regulation of keratinocyte differentiation negative regulation of transcription regulatory region DNA binding embryonic limb morphogenesis frontal suture morphogenesis mammary gland epithelium development BMP signaling pathway involved in heart development enamel mineralization Osifikaciya anterior posterior pattern specification bone morphogenesis GO 0009373 regulation of transcription DNA templated cellular response to growth factor stimulus activation of meiosis endochondral bone growth wound healing spreading of epidermal cells BMP signaling pathway embryonic digit morphogenesis positive regulation of mesenchymal cell apoptotic process multicellular organism development embryonic hindlimb morphogenesis negative regulation of CREB transcription factor activity outflow tract morphogenesis bone trabecula formation Zagoyennya ran regulation of apoptotic process chondrocyte development osteoblast development positive regulation of osteoblast differentiation cranial suture morphogenesis negative regulation of fat cell differentiation branching involved in mammary gland duct morphogenesis outflow tract septum morphogenesis GO 0045996 negative regulation of transcription DNA templated osteoblast differentiation epithelial to mesenchymal transition involved in endocardial cushion formation positive regulation of BMP signaling pathway signal transduction involved in regulation of gene expression cellular response to estradiol stimulus embryonic forelimb morphogenesis embryonic nail plate morphogenesis negative regulation of apoptotic process cartilage development stem cell differentiation odontogenesis transcription DNA templated GO 1901227 negative regulation of transcription by RNA polymerase II embryonic morphogenesisDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez4488 17702Ensembl ENSG00000120149 n dUniProt P35548 Q03358RefSeq mRNK NM 002449NM 001363626NM 013601RefSeq bilok NP 002440NP 001350555NP 038629Lokus UCSC Hr 5 174 72 174 73 Mbn dPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLSA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do represoriv bilkiv rozvitku Zadiyanij u takih biologichnih procesah yak transkripciya regulyaciya transkripciyi osteogenez polimorfizm Bilok maye sajt dlya zv yazuvannya z DNK Lokalizovanij u yadri Literatura red Hodgkinson J E Davidson C L Beresford J Sharpe P T 1993 Expression of a human homeobox containing gene is regulated by 1 25 OH 2D3 in bone cells Biochim Biophys Acta 1174 11 16 PubMed DOI 10 1016 0167 4781 93 90086 S The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Iimura T 1994 Molecular cloning and expression of homeobox containing genes during hard tissue development Kokubyo Gakkai Zasshi 61 590 604 PubMedPrimitki red Zahvoryuvannya genetichno pov yazani z MSX2 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 7392 angl Procitovano 31 serpnya 2017 UniProt P35548 angl Arhiv originalu za 30 serpnya 2017 Procitovano 31 serpnya 2017 Div takozh red Hromosoma 5 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title MSX2 amp oldid 38132564
