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C reaktivnij bilok angl C reactive protein bilok yakij koduyetsya genom CRP roztashovanim u lyudej na korotkomu plechi 1 yi hromosomi 3 Dovzhina polipeptidnogo lancyuga bilka stanovit 224 aminokislot a molekulyarna masa 25 039 4 CRPNayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB1B09 1GNH 1LJ7 3L2Y 3PVN 3PVOIdentifikatoriSimvoliCRP PTX1 C reactive protein pentraxin related C Reactive ProteinZovnishni ID OMIM 123260 MGI 88512 HomoloGene 128039 GeneCards CRPOntologiya genaMolekulyarna funkciya low density lipoprotein particle receptor binding calcium ion binding virion binding complement component C1q complex binding GO 0001948 GO 0016582 protein binding zv yazuvannya z ionom metalu low density lipoprotein particle binding choline binding identical protein bindingKlitinna komponenta extracellular region extracellular spaceBiologichnij proces negative regulation of lipid storage positive regulation of superoxide anion generation GO 1901313 positive regulation of gene expression inflammatory response acute phase response negative regulation of macrophage derived foam cell differentiation Opsonizaciya GO 0051637 defense response to Gram positive bacterium complement activation classical pathway Vrodzhenij imunitetDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez1401 12944Ensembl ENSG00000132693 ENSMUSG00000037942UniProt P02741 P14847RefSeq mRNK NM 000567NM 001329057NM 001329058NM 001382703NM 007768RefSeq bilok NP 000558NP 001315986NP 001315987NP 001369632NP 031794Lokus UCSC Hr 1 159 71 159 71 MbHr 1 172 53 172 66 MbPubMed search 1 2 VikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWPA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Zadiyanij u takomu biologichnomu procesi yak gostra faza zapalennya Bilok maye sajt dlya zv yazuvannya z ionami metaliv ionom kalciyu Sekretovanij nazovni Literatura RedaguvatiThe status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Whitehead A S Bruns G A P Markham A F Colten H R Woods D E 1983 Isolation of human C reactive protein complementary DNA and localization of the gene to chromosome 1 Science 221 69 71 PubMed DOI 10 1126 science 6857266 Osmand A P Gewurz H Friedenson B 1977 Partial amino acid sequences of human and rabbit C reactive proteins homology with immunoglobulins and histocompatibility antigens Proc Natl Acad Sci U S A 74 1214 1218 PubMed DOI 10 1073 pnas 74 3 1214 Thompson D Pepys M B Wood S P 1999 The physiological structure of human C reactive protein and its complex with phosphocholine Structure 7 169 177 PubMed DOI 10 1016 S0969 2126 99 80023 9 Woo P Korenberg J R Whitehead A S 1985 Characterization of genomic and complementary DNA sequence of human C reactive protein and comparison with the complementary DNA sequence of serum amyloid P component J Biol Chem 260 13384 13388 PubMed Oliveira E B Gotschlich E C Liu T Y 1979 Primary structure of human C reactive protein J Biol Chem 254 489 502 PubMedPrimitki Redaguvati Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 2367 angl Arhiv originalu za 23 grudnya 2017 Procitovano 25 serpnya 2017 UniProt P02741 angl Arhiv originalu za 27 serpnya 2017 Procitovano 25 serpnya 2017 Div takozh RedaguvatiHromosoma 1 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title C reaktivnij bilok amp oldid 35580351