Keratin 5 angl Keratin 5 bilok yakij koduyetsya genom KRT5 roztashovanim u lyudej na korotkomu plechi 12 yi hromosomi 4 Dovzhina polipeptidnogo lancyuga bilka stanovit 590 aminokislot a molekulyarna masa 62 378 5 Keratin 5Nayavni strukturiPDBPoshuk ortologiv PDBe RCSBSpisok kodiv PDB3TNUIdentifikatoriSimvoliKRT5 CK5 DDD DDD1 EBS2 K5 KRT5A keratin 5 EBS2E EBS2B EBS2C EBS1 EBS2A EBS2F EBS2DZovnishni ID OMIM 148040 MGI 96702 HomoloGene 55461 GeneCards KRT5Pov yazani genetichni zahvoryuvannyabasal cell carcinoma epidermolysis bullosa herpetiformis localized epidermolysis bullosa simplex generalized epidermolysis bullosa simplex Dowling Degos disease 1 Ontologiya genaMolekulyarna funkciya scaffold protein binding structural constituent of cytoskeleton GO 0001948 GO 0016582 protein binding structural molecule activityKlitinna komponenta citoplazma gialoplazma klitinna membrana keratin filament ekzosoma Promizhni filamenti membrana mitohondriya klitinne yadroBiologichnij proces hemidesmosome assembly epidermis development cytoskeleton organization keratinization cornificationDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez3852 110308Ensembl ENSG00000186081 ENSMUSG00000061527UniProt P13647 Q922U2RefSeq mRNK NM 000424NM 027011RefSeq bilok NP 000415NP 081287Lokus UCSC Hr 12 52 51 52 52 MbHr 15 101 62 101 62 MbPubMed search 2 3 VikidaniDiv Red dlya lyudejDiv Red dlya mishejNalezhit do velikoyi rodini keratiniv strukturnih bilkiv citoskeletu Poslidovnist aminokislot1020304050MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKSA Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y TirozinLiteratura red Eckert R L Rorke E A 1988 The sequence of the human epidermal 58 kD 5 type II keratin reveals an absence of 5 upstream sequence conservation between coexpressed epidermal keratins DNA 7 337 345 PubMed DOI 10 1089 dna 1 1988 7 337 Lersch R Stellmach V Stocks X Giudice G Fuchs E 1989 Isolation sequence and expression of a human keratin K5 gene transcriptional regulation of keratins and insights into pairwise control Mol Cell Biol 9 3685 3697 PubMed DOI 10 1128 MCB 9 9 3685 Whittock N V Eady R A J McGrath J A 2000 Genomic organization and amplification of the human epidermal type II keratin genes K1 and K5 Biochem Biophys Res Commun 274 149 152 PubMed DOI 10 1006 bbrc 2000 3110 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PubMed DOI 10 1101 gr 2596504 Lersch R Fuchs E 1988 Sequence and expression of a type II keratin K5 in human epidermal cells Mol Cell Biol 8 486 493 PubMed DOI 10 1128 MCB 8 1 486 Xu Z Dong H Sun X Zhu X Yang Y 2004 A new keratin 5 mutation K199T in a family with Weber Cockayne epidermolysis bullosa simplex Clin Exp Dermatol 29 74 76 PubMed DOI 10 1111 j 1365 2230 2004 01434 xPrimitki red Zahvoryuvannya genetichno pov yazani z Keratin 5 pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference HUGO Gene Nomenclature Commitee HGNC 6442 angl Arhiv originalu za 28 chervnya 2017 Procitovano 30 sichnya 2017 UniProt P13647 angl Arhiv originalu za 6 lyutogo 2017 Procitovano 30 sichnya 2017 Div takozh red Hromosoma 12 nbsp Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi Otrimano z https uk wikipedia org w index php title Keratin 5 amp oldid 36272309
